Development of Fibroblast Activation Protein Inhibitor-Based Dimeric Radiotracers with Improved Tumor Retention and Antitumor Efficacy
Liang Zhao, Jianhao Chen, Yizhen Pang, Jianyang Fang, Kaili Fu, Lingxin Meng, Xianzhong Zhang, Zhide Guo, Hua Wu, Long Sun, Guoqiang Su, Qin Lin, Haojun Chen
Abstract
may be safe and effective for the treatment of FAP-positive malignant tumors.
Topics & Concepts
Fibroblast activation protein, alphaChemistryCancer researchFibroblastPharmacologyBiochemistryCancerMedicineIn vitroInternal medicinePeptidase Inhibition and AnalysisProtease and Inhibitor MechanismsCardiac Structural Anomalies and Repair