Electrochemical response of surface-attached redox DNA governed by low activation energy electron transfer kinetics
Zhiyong Zheng, Soo Hyeon Kim, Arnaud Chovin, Nicolas Clément, Christophe Demaille
Abstract
the DNA chain. This so far unreported effect, that we attribute to a slower relaxation of water around Fc, uniquely shapes the electrochemical response of Fc-DNA strands and, being markedly dissimilar for single-stranded and duplexed DNA, contributes to the signaling mechanism of E-DNA sensors.
Topics & Concepts
ElectrochemistryElectron transferRedoxChemistryElectrodeOligonucleotideKineticsFerroceneCyclic voltammetryElectron transport chainDNAElectrochemical kineticsPhotochemistryInorganic chemistryPhysical chemistryBiochemistryQuantum mechanicsPhysicsAdvanced biosensing and bioanalysis techniquesElectrochemical Analysis and ApplicationsDNA and Nucleic Acid Chemistry