Retinotopic variations of the negative blood-oxygen-level dependent hemodynamic response function in human primary visual cortex
Natasha de la Rosa, David Ress, Amanda J. Taylor, Jung Hwan Kim
Abstract
We investigate dynamics of the negative hemodynamic response function (nHRF), the negative blood-oxygen-level-dependent (BOLD) response (NBR) evoked by a brief stimulus, in human early visual cortex. Here, we show that the nHRFs are not inverted versions of the corresponding pHRFs. The nHRF has complex dynamics that varied significantly with eccentricity. The results also show shift-invariant temporal linearity does not hold for the NBR.
Topics & Concepts
Stimulus (psychology)Visual cortexHaemodynamic responseFunctional magnetic resonance imagingBlood-oxygen-level dependentNeurosciencePsychologyHemodynamicsExcitatory postsynaptic potentialChemistryInhibitory postsynaptic potentialMedicineInternal medicineHeart rateBlood pressureCognitive psychologyFunctional Brain Connectivity StudiesAdvanced MRI Techniques and ApplicationsNeural dynamics and brain function