Checkerboard Analysis To Evaluate Synergistic Combinations of Existing Antifungal Drugs and Propylene Glycol Monocaprylate in Isolates from Recalcitrant Tinea Corporis and Cruris Patients Harboring Squalene Epoxidase Gene Mutation
Kabir Sardana, Aastha Gupta, Suresh Sadhasivam, R. K. Gautam, Ananta Khurana, Swamini Saini, Swati Gupta, Shamik Ghosh
Abstract
synergistic interactions provide a sound scientific basis for the possible clinical use of antifungal combinations. Hence, these synergistic combinations may be tested for clinical utility in the wake of rising resistance among dermatophytic infections of the glabrous skin.
Topics & Concepts
TerbinafineTinea capitisItraconazoleKetoconazoleAntifungalMedicineDermatophyteDermatologyMicrobiologyPharmacologyBiologyNail Diseases and TreatmentsFungal Infections and StudiesAntifungal resistance and susceptibility