Stability Indicating LC Method Development for Hydroxychloroquine Sulfate Impurities as Available for Treatment of COVID-19 and Evaluation of Risk Assessment Prior to Method Validation by Quality by Design Approach
Thirupathi Dongala, Naresh Kumar Katari, Ashok Kumar Palakurthi, Lakshmi Narasimha Rao Katakam, Vishnu Murthy Marisetti
Topics & Concepts
HydroxychloroquineChemistryChromatographyImpurityQuality by DesignHigh-performance liquid chromatographyCalibration curveDosage formAccuracy and precisionDetection limitCoronavirus disease 2019 (COVID-19)MathematicsParticle sizeStatisticsOrganic chemistryPathologyDiseaseInfectious disease (medical specialty)MedicinePhysical chemistryAntibiotics Pharmacokinetics and EfficacyAnalytical Methods in PharmaceuticalsAnalytical Chemistry and Chromatography