Novel triazole-tethered thiazol-4(5H)-one hybrids as potential therapeutics for obesity and type 2 diabetes: in vitro, in vivo, and in silico evaluations
Walaa I. El-Sofany, Amani Toumi, Ismail Daoud, Saoussen Haddad, Salman Latif, Ahlam F. Alshammari, Mona Zaheed Alshammari, Hissah Khashman Alshammari, Nawal S. Alshammari, Sarra Boudriga, Khaled Hamden
Topics & Concepts
ChemistryIn silicoIn vivoIn vitroType 2 diabetesTriazolePharmacologyCombinatorial chemistryComputational biologyDiabetes mellitusBiochemistryBiotechnologyOrganic chemistryEndocrinologyGeneMedicineBiologyClick Chemistry and ApplicationsSynthesis and biological activityChemical Synthesis and Analysis