Synthesis of Tetrahydroquinolines via Borrowing Hydrogen Methodology Using a Manganese PN<sup>3</sup> Pincer Catalyst
Natalie Hofmann, Leonard Homberg, Kai C. Hultzsch
Abstract
pincer complex. The reaction selectively leads to 1,2,3,4-tetrahydroquinolines thanks to a targeted choice of base. This strategy provides an atom-efficient pathway with water as the only byproduct. In addition, no further reducing agents are required.
Topics & Concepts
ChemistryPincer movementCatalysisManganeseCombinatorial chemistryCascade reactionCascadeHydrogenBase (topology)Organic chemistryMathematicsMathematical analysisChromatographyAsymmetric Hydrogenation and CatalysisChemical Synthesis and AnalysisNanomaterials for catalytic reactions