Multiligand-enabled, copper-catalyzed Hiyama coupling of arylsilanes with unactivated secondary alkyl halides: reaction development and mechanistic insights
Jiajing Zhou, Zhiqiang Zhang, Yan Cao, Weilong Xie
Abstract
A multiligand-involved Cu catalysis offers an efficient Hiyama coupling of arylsilanes with unactivated alkyl halides, where copper with NHC and phenanthroline ligands were account for C(sp 2 )–Si activation and C(sp 2 )–C(sp 3 ) formation, respectively.
Topics & Concepts
HalideAlkylChemistryCatalysisCopperCoupling reactionCoupling (piping)Combinatorial chemistryPolymer chemistryOrganic chemistryMaterials scienceMetallurgyCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques