In vitro antitumor effect of cucurbitacin E on human lung cancer cell line and its molecular mechanism
Siyuan Jing, Zidan Wu, Tiehua Zhang, Jie Zhang, Zhengyi Wei
Topics & Concepts
SurvivinMAPK/ERK pathwayEpidermal growth factor receptorCell cycleApoptosisEpidermal growth factorCancer researchKinaseSignal transductionCell biologyPhosphorylationA549 cellCaspaseCell growthA431 cellsTyrosine kinaseCell cycle checkpointChemistryBiologyCell cultureProgrammed cell deathReceptorMolecular medicineBiochemistryGeneticsAdvances in Cucurbitaceae ResearchBioactive Compounds and Antitumor AgentsProtein Tyrosine Phosphatases