Novel Quinolone Derivatives: Synthesis and Antioxidant Activity
Mutyala Veera Venkata Vara Prasad, Radha Hunasenahalli Raghavendra Rao, Vadde Veeranna, Venkata Suryanarayana Chennupalli, Byrappa Sathish
Abstract
Novel quinolone derivatives have been designed and readily synthesized according to a simple protocol including O-alkylation and Claisen rearrangement processes. Structures of the synthesized compounds have been confirmed by IR, 1H and 13C NMR, and mass spectra. The new products have been tested for their antioxidant activity, and two of those demonstrate high antioxidant activity.
Topics & Concepts
ChemistryAntioxidantQuinoloneAlkylationClaisen rearrangementCarbon-13 NMRCombinatorial chemistryProton NMRStereochemistryOrganic chemistryBiochemistryCatalysisAntibioticsSynthesis and biological activitySynthesis and Biological EvaluationBioactive Compounds and Antitumor Agents