Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer
Yun Zhu, Alfred K. Lam, Daisy Kwok‐Yan Shum, Di Cui, Jun Zhang, Dongdong Yan, Bin Li, Wen Xu, Nikki P.Y. Lee, Kin Chan, Simon Law, Sai Wah Tsao, Annie L.M. Cheung
Abstract
: This study provides the first evidence that elevated serum SRGN has prognostic significance in patients with ESCC, and sheds light on the molecular mechanism by which elevated circulating SRGN in cancer patients might promote cancer progression.
Topics & Concepts
Esophageal cancerMetastasisCancer researchCancerAutocrine signallingChemistryMedicineInternal medicineReceptorProteoglycans and glycosaminoglycans researchFibroblast Growth Factor ResearchGlycosylation and Glycoproteins Research