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Buffered lidocaine 1%/epinephrine 1:100,000 with sodium bicarbonate (sodium hydrogen carbonate) in a 3:1 ratio is less painful than a 9:1 ratio: A double-blind, randomized, placebo-controlled, crossover trial

Alexandra Vent, Christian Surber, Nicole Tracy Graf Johansen, Verena Figueiredo, Georg Schönbächler, Laurence Imhof, Caroline Buset, Jürg Hafner

2020Journal of the American Academy of Dermatology40 citationsDOIOpen Access PDF

Topics & Concepts

MedicineSodium bicarbonateEpinephrineAnesthesiaPlaceboLidocaineSodiumRandomized controlled trialDouble blindBicarbonateInternal medicineOrganic chemistryAlternative medicinePathologyChemistryPediatric Pain Management TechniquesThermal Regulation in MedicineDental Anxiety and Anesthesia Techniques
Buffered lidocaine 1%/epinephrine 1:100,000 with sodium bicarbonate (sodium hydrogen carbonate) in a 3:1 ratio is less painful than a 9:1 ratio: A double-blind, randomized, placebo-controlled, crossover trial | Litcius