Deficiency of tenascin-C attenuated cardiac injury by inactivating TLR4/NLRP3/caspase-1 pathway after myocardial infarction
Mingyue Xu, Zhishuai Ye, Xin Zhao, Hongzhou Guo, Xuhe Gong, Rongchong Huang
Topics & Concepts
PyroptosisDownregulation and upregulationProinflammatory cytokineCaspase 1InflammationTLR4ApoptosisGene knockdownImmunostainingMedicineKnockout mouseWestern blotEndocrinologyInternal medicineMolecular biologyChemistryBiologyInflammasomeBiochemistryImmunohistochemistryReceptorGeneInflammasome and immune disordersStreptococcal Infections and TreatmentsKawasaki Disease and Coronary Complications