<p>Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review</p>
Yayun Xu, Feihu Chen
Abstract
Nesfatin-1, a newly identified energy-regulating peptide, is widely expressed in the central and peripheral tissues, and has a variety of physiological activities. A large number of recent studies have shown that nesfatin-1 exhibits antioxidant, anti-inflammatory, and anti-apoptotic properties and is involved in the occurrence and progression of various diseases. This review summarizes current data focusing on the therapeutic effects of nesfatin-1 under different pathophysiological conditions and the mechanisms underlying its antioxidant, anti-inflammatory, and anti-apoptotic activities.
Topics & Concepts
ApoptosisAntioxidantInflammationChemistryMolecular biologyInternal medicinePharmacologyEndocrinologyBiologyMedicineBiochemistryAdipokines, Inflammation, and Metabolic DiseasesAntioxidant Activity and Oxidative StressRegulation of Appetite and Obesity