Pathway-directed recyclable chirality inversion of coordinated supramolecular polymers
Kuo Fu, Yanli Zhao, Guofeng Liu
Abstract
It remains challenging to elucidate the fundamental mechanisms behind the dynamic chirality inversion of supramolecular assemblies with pathway complexity. Herein, metal coordination driven assembly systems based on pyridyl-conjugated cholesterol (PVPCC) and metal ions (Ag+ or Al3+) are established to demonstrate pathway-directed, recyclable chirality inversion and assembly polymorphism. In the Ag(I)/PVPCC system, a competitive pathway leads Ag-Complex to form either kinetically controlled supramolecular polymer (Ag-SP I) or thermodynamically favored Ag-SP II, accompanied by reversible chiroptical inversion. Conversely, the Al(III)/PVPCC system displays a solvent-assisted consecutive pathway: the Al-Complex initially forms ethanol-containing Al-SP II, and subsequently converts into ethanol-free Al-SP I with opposite chiroptical performance upon thermal treatment. Moreover, stable chirality inversion in the solid state enables potential dynamic circularly polarized luminescence encryption when Ag(I)/PVPCC is co-assembled with thioflavin T. These findings provide the guidance for the dynamic modulation of chirality functionality in supramolecular materials for applications in information processing, data encryption, and chiral spintronics. Elucidation of the fundamental mechanisms behind the dynamic chirality inversion of supramolecular assemblies with pathway complexity is challenging. Here, the authors report metal coordination driven assembly systems based on pyridyl-conjugated cholesterol and show that metal ions facilitate pathway-directed, recyclable chirality inversion and assembly polymorphism.