Myricetin: A comprehensive review on its biological potentials
Muhammad Imran, Farhan Saeed, Ghulam Hussain, Ali Imran, Zaffar Mehmood, Tanweer Aslam Gondal, Ahmed H. El‐Ghorab, Ishtiaque Ahmad, Raffaele Pezzani, Muhammad Umair Arshad, Umar Bacha, Mohammad Ali Shariarti, Abdur Rauf, Naveed Muhammad, Zafar Ali Shah, Gökhan Zengin, Saiful Islam
Abstract
Abstract Myricetin is a critical nutritive component of diet providing immunological protection and beneficial for maintaining good health. It is found in fruits, vegetables, tea, and wine. The families Myricaceae , Polygonaceae , Primulaceae , Pinaceae, and Anacardiaceae are the richest sources of myricetin. Different researchers explored the therapeutic potential of this valuable constituent such as anticancer, antidiabetic, antiobesity, cardiovascular protection, osteoporosis protection, anti‐inflammatory, and hepatoprotective. In addition to these, the compound has been tested for cancer and diabetic mellitus during clinical trials. Health benefits of myricetin are related to its impact on different cell processes, such as apoptosis, glycolysis, cell cycle, energy balance, lipid level, serum protein concentrations, and osteoclastogenesis. This review explored the potential health benefits of myricetin with a specific emphasis on its mechanism of action, considering the most updated and novel findings in the field.