Identification of dual inhibitor of phosphodiesterase 1B/10A using structure-based drug design approach
Mayasah Al‐Nema, Anand Gaurav, Vannajan Sanghiran Lee, Baskaran Gunasekaran, Ming Tatt Lee, Patrick Nwabueze Okechukwu
Topics & Concepts
Dopamine receptor D2PharmacophoreSchizophrenia (object-oriented programming)DopaminePhosphodiesteraseDopamine hypothesis of schizophreniaDopamine receptorPharmacologyDopamine receptor D1Virtual screeningPDE10ANeurosciencePsychologyMedicinePsychiatryBioinformaticsChemistryBiologyEnzymeBiochemistryPhosphodiesterase function and regulationReceptor Mechanisms and SignalingCholinesterase and Neurodegenerative Diseases