A brief overview of classical natural product drug synthesis and bioactivity
Gen Li, Mingliang Lou, Xiangbing Qi
Abstract
This manuscript briefly overviewed the total synthesis and structure–activity relationship studies of eight classical natural products, which emphasizes the important role of total synthesis in natural product-based drug development.
Topics & Concepts
Natural productChemistryTotal synthesisNatural (archaeology)DrugProduct (mathematics)Biochemical engineeringCombinatorial chemistryPharmacologyStereochemistryEngineeringMathematicsGeographyMedicineArchaeologyGeometryMicrobial Natural Products and BiosynthesisSynthesis and Biological ActivityMarine Sponges and Natural Products