AAV vector-derived elements integrate into Cas9-generated double-strand breaks and disrupt gene transcription
Hannah O Bazick, Hanqian Mao, Jesse K. Niehaus, Justin M. Wolter, Mark J. Zylka
Topics & Concepts
Transcription (linguistics)BiologyGeneVector (molecular biology)GeneticsComputational biologyDouble strandCas9CRISPRCell biologyRecombinant DNADNA repairLinguisticsPhilosophyCRISPR and Genetic EngineeringVirus-based gene therapy researchRNA regulation and disease