Activating Transcription Factor 4-mediated Mitochondrial Unfolded Protein Response Alleviates Hippocampal Neuronal Damage in an In Vitro Model of Epileptiform Discharges
Xiaomeng Yu, Xiaoyi Wang, Yinyin Xie, Tingting Peng, Yajun Lian, Cui Wang, Nanchang Xie
Topics & Concepts
ATF4Unfolded protein responseCell biologyIntegrated stress responseBiologyTransfectionHSP60Reactive oxygen speciesApoptosisChemistryMolecular biologyCell cultureHeat shock proteinHsp70Messenger RNABiochemistryTranslation (biology)Endoplasmic reticulumGeneGeneticsMitochondrial Function and PathologyEndoplasmic Reticulum Stress and DiseaseAlzheimer's disease research and treatments