Cu(II)-acylhydrazone complex, a potent and selective antitumor agent against human osteosarcoma: Mechanism of action studies over in vitro and in vivo models
Lucía M. Balsa, Luisina M. Solernó, María R. Rodríguez, Beatriz S. Parajón‐Costa, Ana C. González‐Baró, Daniel F. Alonso, Juan Garona, Ignácio E. León
Topics & Concepts
In vivoCisplatinChemistryOsteosarcomaIn vitroCancer researchApoptosisPharmacologyCell cultureComet assayCell growthBiochemistryBiologyMedicineChemotherapyDNA damageInternal medicineDNAGeneticsBiotechnologyMetal complexes synthesis and propertiesFerrocene Chemistry and ApplicationsDendrimers and Hyperbranched Polymers