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DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer

Xiangling Chen, Peng Liu, Weiliang Zhu, Liguang Lou

2020Acta Pharmacologica Sinica24 citationsDOIOpen Access PDF

Topics & Concepts

AutophagyCancer researchCancer cellChemistryHsp90 inhibitorProtein kinase BPI3K/AKT/mTOR pathwayCell biologyBiologyHsp90ApoptosisCancerSignal transductionBiochemistryHeat shock proteinGeneticsGeneAutophagy in Disease and TherapyHeat shock proteins researchSirtuins and Resveratrol in Medicine
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer | Litcius