Metal–organic framework-based oxygen carriers with antioxidant activity resulting from the incorporation of gold nanozymes
Xiaoli Liu, Nency P. Domingues, Emad Oveisi, Clara Coll-Satue, Michelle Maria Theresia Jansman, Berend Smit, Leticia Hosta‐Rigau
Abstract
, hydrogen peroxide and the superoxide radical). Importantly, following loading with Hb, we show how these ROS-scavenging properties translate into a decrease in metHb content. All in all, these results highlight the potential of NZs to create novel HBOCs with antioxidant protection which may find applications as a blood substitute in the future.
Topics & Concepts
MethemoglobinChemistryAntioxidantAutoxidationReactive oxygen speciesHydrogen peroxideContext (archaeology)HemoglobinBiocompatibilityOxygenSuperoxide dismutaseNanocarriersCombinatorial chemistryBiochemistryOrganic chemistryDrug deliveryPaleontologyBiologyAdvanced Nanomaterials in CatalysisNanoplatforms for cancer theranosticsNanoparticle-Based Drug Delivery