Nucleosides and Nucleoside Analogues as Emerging Antiviral Drugs
Mohamed I. Elzagheid
Abstract
Nucleosides and their analogues have been in use for many years and have become essential for treating patients with viral infections. Many additional nucleoside drugs have been approved over the past decades. This strongly demonstrates how important these compounds are and the crucial role they play. Given that a significant amount of research and literature has been documented regarding nucleoside analogues, this review article mainly focuses on nucleosides and nucleoside analogues that have proven to play a significant role in the treatment of known viral infections. This article covers the names, structures, applications, toxicity, and mode of action of relevant nucleoside analogues.
Topics & Concepts
NucleosideNucleoside analogueMode of actionDrugMedicinePharmacologyChemistryBiologyToxicologyStereochemistryHIV/AIDS drug development and treatmentBiochemical and Molecular ResearchCytomegalovirus and herpesvirus research