Magnetic covalent organic frameworks for extraction and determination of endocrine‐disrupting chemicals in beverage and water samples
Jie Zhao, Ziyu Li, Chun‐Xu Yang, Yaping Li, Yushen Liu, Zhen Hu, Xiaoming Pan, Xiu‐Li Ma, Wei Wang, Xiao‐Shuai Yang, Lu‐Liang Wang
Abstract
Abstract BACKGROUND Phenolic endocrine‐disrupting chemicals (EDCs) are widespread and easily ingested through the food chain. They pose a serious threat to human health. Magnetic solid‐phase extraction (MSPE) is an effective sample pre‐treatment technology to determine traces of phenolic EDCs. RESULTS Magnetic covalent organic framework (COF) (Fe 3 O 4 @COF) nanospheres were prepared and characterized. The efficient and selective extraction of phenolic EDCs relies on a large specific surface and the inherent porosity of COFs and hydrogen bonding, π–π, and hydrophobic interactions between COF shells and phenolic EDCs. Under optimal conditions, the proposed magnetic solid‐phase extraction‐high‐performance liquid chromatography–ultra violet (MSPE‐HPLC‐UV) based on the metallic covalent organic framework method for phenolic EDCs shows good linearities (0.002–6 μg mL −1 ), with R 2 of 0.995 or higher, and low limits of detection (6–1.200 ng mL −1 ). CONCLUSION Magnetic covalent organic frameworks (Fe 3 O 4 @COFs) with good MSPE performance for phenolic EDCs were synthesized by the solvothermal method. The magnetic covalent organic framework‐based MSPE‐HPLC‐UV method was applied successfully to determine phenolic EDCs in beverage and water samples with satisfactory recoveries (90.200%–123%) and relative standard deviations (2.100%–12.100%). © 2023 Society of Chemical Industry.