Probucol attenuates NF-κB/NLRP3 signalling and augments Nrf-2 mediated antioxidant defence in nerve injury induced neuropathic pain
Kalyani Derangula, Mohit Javalgekar, Vijay Arruri, Chayanika Gundu, Anil Kumar Kalvala, Ashutosh Kumar
Topics & Concepts
Neuropathic painOxidative stressProinflammatory cytokinePharmacologyNeuroinflammationMedicineSciatic nerveNerve injuryInflammationNF-κBNeuroprotectionSciatic nerve injuryEndocrinologyInternal medicineAnesthesiaPain Mechanisms and TreatmentsPharmacological Effects of Natural CompoundsExercise and Physiological Responses