Catalyst-controlled and visible light-induced acylmethylation and bromoacylmethylation of Morita–Baylis–Hillman acetates with α-bromo ketones: access to highly functionalized 1,5-dicarbonyl compounds
De‐Run Zhang, Lin‐Ping Hu, Fenglin Liu, Xiao‐Hong Huang, Xia Li, Bo Liu, Ming‐Yu Teng, Guoli Huang
Abstract
Catalyst-controlled and photoinduced acylmethylation and bromoacylmethylation of Morita–Baylis–Hillman acetates with α-bromo ketones to construct highly functionalized 1,5-dicarbonyls with high yields, chemo- and regio-selectivities were reported.
Topics & Concepts
ChemistryCatalysisMorita therapyBaylis–Hillman reactionOrganic chemistryMedicinal chemistryCombinatorial chemistryPsychoanalysisPsychologyRadical Photochemical ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods