N2L, a novel lipoic acid-niacin dimer, attenuates ferroptosis and decreases lipid peroxidation in HT22 cells
Weijia Peng, Zeyu Zhu, Yang Yang, Jiawei Hou, Junfeng Lu, Chen Chen, Fang Liu, Rongbiao Pi
Topics & Concepts
GPX4Lipid peroxidationChemistryReactive oxygen speciesKinaseMAPK/ERK pathwayCytoprotectionProgrammed cell deathCell biologyDownregulation and upregulationNeuroprotectionBiochemistryOxidative stressPharmacologyGlutathione peroxidaseBiologySuperoxide dismutaseApoptosisGeneFerroptosis and cancer prognosisEpigenetics and DNA MethylationGDF15 and Related Biomarkers