Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing
Daniel L. Kober, Arun Radhakrishnan, Joseph L. Goldstein, Michael S. Brown, Lindsay Clark, Xiao‐chen Bai, Daniel M. Rosenbaum
Topics & Concepts
BiologyEndoplasmic reticulumSterol regulatory element-binding proteinCell biologyGolgi apparatusTransmembrane domainSterolBiophysicsTransmembrane proteinCholesterolMutantPlasma protein bindingBiochemistryMembraneGeneReceptorRNA and protein synthesis mechanismsCholesterol and Lipid MetabolismLipid Membrane Structure and Behavior