Pre-conditioning modifies the TME to enhance solid tumor CAR T cell efficacy and endogenous protective immunity
John P. Murad, Dileshni Tilakawardane, Anthony K. Park, Lupita S. Lopez, Cari A. Young, Jackson Gibson, Yukiko Yamaguchi, Hee Jun Lee, Kelly T. Kennewick, Brenna Gittins, Wen-Chung Chang, Chau P. Tran, Catalina Martínez, Anna M. Wu, Robert E. Reiter, Tanya B. Dorff, Stephen J. Forman, Saul J. Priceman
Topics & Concepts
Cancer researchChimeric antigen receptorTumor microenvironmentProstate cancerImmunologyMedicineAntigenImmune systemT cellImmunotherapyCancerBiologyInternal medicineCAR-T cell therapy researchImmunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers