Suppression of asparagine synthetase enhances the antitumor potency of ART and artemalogue SOMCL-14-221 in non-small cell lung cancer
Ruoxuan Xiao, Chunyong Ding, Hongwen Zhu, Xia Liu, Jing Gao, Qian Liu, Dayun Lu, Naixia Zhang, Ao Zhang, Hu Zhou
Topics & Concepts
Unfolded protein responseA549 cellCancer researchCell growthLung cancerIn vivoDownregulation and upregulationCellChemistryEndoplasmic reticulumPharmacologyBiologyMedicineBiochemistryInternal medicineBiotechnologyGeneEndoplasmic Reticulum Stress and DiseaseUbiquitin and proteasome pathwaysProtein Structure and Dynamics