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Is Weight Loss–Induced Muscle Mass Loss Clinically Relevant?

Caterina Conte, Kevin D. Hall, Samuel Klein

2024JAMA167 citationsDOI

Abstract

This Viewpoint explores the effects of weight loss achieved through GLP-1–based antiobesity medications on weight regain, fat-free mass, and skeletal muscle mass in people with obesity.

Topics & Concepts

MedicineWeight lossMuscle massSkeletal muscleFat massObesityInternal medicineEndocrinologyPharmacology and Obesity TreatmentEating Disorders and BehaviorsMuscle metabolism and nutrition
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