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Synthesis of substituted benzylboronates by light promoted homologation of boronic acids with <i>N</i> -sulfonylhydrazones

Álvaro Valdés‐Maqueda, Lucía López, Manuel Plaza, Carlos Valdés

2023Chemical Science28 citationsDOIOpen Access PDF

Abstract

The homologation of boronic acids with diazoalkanes obtained by photochemical decomposition of N -tosylhydrazones leads to substituted benzylboronates, previously unavailable under thermal conditions. Batch and continuous flow reactions are described.

Topics & Concepts

ChemistryBoronic acidCombinatorial chemistrySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods
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