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Integrate bubble flotation and intermittent microbubble-enhanced cold plasma activation for scalable disinfection of food processing wastewater

Deepak Panchal, Qiuyun Lu, Ziya Saedi, Herman Luk, Tong Yu, Xuehua Zhang

2025Separation and Purification Technology12 citationsDOIOpen Access PDF

Abstract

• Clean plasma-bubble approach remove Gram-(+/-) in complex water matrices. • Pretreatment flotation reduces turbidity (66%), non-targeted organics (57%) in wastewater. • Intermittent MB-CPA led 6-log E. coli removal in meat-processing wastewater. • Complete inactivation of antibiotic-resistant pathogens (MRSA) at 5.7-log reduction. • Integrated MB-CPA and flotation offer scalable disinfection of complex wastewater. The food processing industry is one of the largest global consumers of potable water, generating vast volumes of pathogen-rich wastewater that pose significant treatment challenges. Cold plasma activation has emerged as a promising technology for water disinfection; however, scalability remains a critical limitation. In this study, we address this challenge by developing an integrated approach that combines flotation-based pre-treatment with intermittent microbubble-enhanced cold plasma activation (MB-CPA) for effective disinfection at varying scales. The pre-treatment step significantly reduces turbidity (∼66 %) and organic load (∼57 %) in wastewater, minimizing interference during disinfection. The novel intermittent MB-CPA technique then enables enhanced antibacterial action, achieving ∼6-log CFU/mL reduction of Gram-positive, Gram-negative, and antibiotic-resistant bacteria in both simulated and real wastewater, with a 1.3-fold increase in efficacy against E. coli compared to continuous CPA. Rapid inactivation was achieved in 10–15 min, with successful scale-up from small volumes (0.5–3.5 L, ∼ 5.7-log CFU/mL reduction) to larger volumes (10 L, ∼ 5-log CFU/mL reduction), and a strong linear relationship (R 2 = 0.96) between volume and exposure time highlights the scalability and feasibility of this method. This integrated system provides a transformative strategy for scalable, efficient disinfection in the meat processing industry, offering a viable solution to the critical challenge of scaling cold plasma-based water treatment for industrial applications.

Topics & Concepts

WastewaterBubbleScalabilityPlasmaWaste managementEnvironmental scienceProcess engineeringChemistryNanotechnologyMaterials scienceEngineeringComputer sciencePhysicsDatabaseQuantum mechanicsParallel computingPlasma Applications and DiagnosticsMercury impact and mitigation studiesWater Treatment and Disinfection