Membrane Proteins and Membrane Curvature: Mutual Interactions and a Perspective on Disease Treatments
Peng Xie, Heng Zhang, Yatong Qin, Hehe Xiong, Changrong Shi, Zijian Zhou
Abstract
The pathogenesis of various diseases often involves an intricate interplay between membrane proteins and membrane curvature. Understanding the underlying mechanisms of this interaction could offer novel perspectives on disease treatment. In this review, we provide an introduction to membrane curvature and its association with membrane proteins. Furthermore, we delve into the impact and potential implications of this interaction in the context of disease treatment. Lastly, we discuss the prospects and challenges associated with harnessing these interactions for effective disease management, aiming to provide fresh insights into therapeutic strategies.
Topics & Concepts
Membrane curvatureContext (archaeology)DiseasePerspective (graphical)MembraneMembrane proteinComputational biologyBiologyMedicineComputer sciencePathologyBiochemistryArtificial intelligenceLipid bilayerPaleontologyCellular transport and secretionLipid Membrane Structure and BehaviorEndoplasmic Reticulum Stress and Disease