PAX3-FOXO1 coordinates enhancer architecture, eRNA transcription, and RNA polymerase pause release at select gene targets
Susu Zhang, Jing Wang, Qi Liu, W. Hayes McDonald, Monica Bomber, Hillary M. Layden, Jacob Ellis, Scott C. Borinstein, Scott W. Hiebert, Kristy R. Stengel
Topics & Concepts
EnhancerBiologyTranscription factorEnhancer RNAsRNA polymerase IIPAX3ChromatinGene expressionTranscription (linguistics)GeneActivator (genetics)GeneticsCell biologyPromoterComputational biologyLinguisticsPhilosophyGenomics and Chromatin DynamicsCRISPR and Genetic EngineeringProtein Degradation and Inhibitors