Lighting up metallohelices: from DNA binders to chemotherapy and photodynamic therapy
Xuezhao Li, Zhuolin Shi, Jinguo Wu, Jinlong Wu, Cheng He, Xiaorou Hao, Chunying Duan
Abstract
quantum yield may provide new motivation in diagnostic and photodynamic therapy (PDT) areas. This perspective focuses on research progress on metallohelices as DNA binders and chemotherapeutic agents, and highlights recent advances in fabricating luminescent examples for PDT. The relative assembly strategies are also discussed and compared. Finally, perspectives on the future development of the lit-up metallohelices are presented.
Topics & Concepts
Photodynamic therapyNanotechnologyDNADNA origamiChemistryCombinatorial chemistryMaterials scienceComputer scienceComputational biologyBiologyBiochemistryOrganic chemistryMagnetism in coordination complexesSupramolecular Chemistry and ComplexesMetal complexes synthesis and properties