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Investigation of Electronic Signal Processing Chains for a Prototype TOF-PET System With 100-ps Coincidence Time Resolution

Shirin Pourashraf, Andrea González-Montoro, Min Sun Lee, Joshua W. Cates, Jun Yeon Won, Jae Sung Lee, Craig S. Levin

2021IEEE Transactions on Radiation and Plasma Medical Sciences20 citationsDOIOpen Access PDF

Abstract

We have evaluated the coincidence time resolution (CTR) performance of four different mixed-signal front-end electronic readout configurations with the goal to achieve 100 picoseconds (ps) CTR. The proposed TOF-PET detector elements are based on two <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$3{\times } 3{\times }10$ </tex-math></inline-formula> mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> “fast LGSO” crystal segments, side coupled to linear arrays of <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$3{\times }3$ </tex-math></inline-formula> mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> silicon photomultipliers (SiPMs), to form a total crystal length of 20 mm. We studied multiple configurations and components for the front-end readout: 1) high speed radio frequency (RF) amplifiers; 2) an ASIC-based discriminator; 3) a combination of RF amplifier, balun transformer, and discriminator ASIC; and 4) combination of balun transformer and discriminator ASIC. Using two <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$3{\times } 3{\times }10$ </tex-math></inline-formula> mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> fast LGSO crystals side coupled to a linear array of three SiPMs, coincidence data were experimentally acquired for each readout configuration in combination with a low jitter field-programmable gate array (FPGA)-based time-to-digital converter (TDC). After evaluating the timing performance of the three readout schemes, the best CTR value of 99.4 ± 1.9 ps FWHM was achieved for configuration (3), which is more than 20 ps better than the results achieved using configurations (1), (2), and (4).

Topics & Concepts

DiscriminatorLyso-Silicon photomultiplierPhysicsAmplifierBalunDetectorTime-to-digital converterApplication-specific integrated circuitOptoelectronicsOpticsElectronic circuitCMOSElectronic engineeringElectrical engineeringEngineeringClock signalScintillatorAntenna (radio)Quantum mechanicsRadiation Detection and Scintillator TechnologiesMedical Imaging Techniques and ApplicationsAtomic and Subatomic Physics Research