Synthesis, antimycobacterial screening, molecular docking, ADMET prediction and pharmacological evaluation on novel pyran-4-one bearing hydrazone, triazole and isoxazole moieties: Potential inhibitors of SARS CoV-2
N. Ravisankar, N. Sarathi, T. Maruthavanan, Subramaniyan Ramasundaram, M. Ramesh, C. Sankar, S. Umamatheswari, G. Kanthimathi, Tae Hwan Oh
Topics & Concepts
ChemistryDNA gyraseDocking (animal)Ethidium bromideAntimycobacterialMycobacterium tuberculosisDNA supercoilStereochemistryTriazoleCombinatorial chemistryDNABiochemistryEscherichia coliDNA replicationTuberculosisOrganic chemistryMedicinePathologyNursingGeneSynthesis and biological activityComputational Drug Discovery MethodsClick Chemistry and Applications