Influence of microchannel geometry on device performance and electrophysiological recording fidelity during long-term studies of connected neural populations
Noah Goshi, Gregory Girardi, Felipe da Costa Souza, Alexander Gardner, Pamela J. Lein, Erkin Şeker
Abstract
This study examines the role of microchannel geometry on the long-term performance of compartmentalized microfluidic neural cell culture platforms and provides general design rules for different experimental objectives.
Topics & Concepts
ElectrophysiologyMicrochannelTerm (time)FidelityPhysicsNeuroscienceComputer scienceMechanicsBiologyTelecommunicationsQuantum mechanicsNeural dynamics and brain functionNeuroscience and Neural EngineeringAdvanced Memory and Neural Computing