Report of two cases of minimal change disease following vaccination for <scp>COVID</scp> ‐19
Krishoban Baskaran, Adrienne Cohen, Nethmi Weerasinghe, Eswari Vilayur
Abstract
of gross haematuria within just 3 h.The transient strongly positive ANA indicates that the COVID-19 vaccination may trigger more generalized immunological response beyond just stimulating IgA production.Reactivation of and new onset lupus nephritis after COVID-19 vaccination with elevated ANA titre have also been reported recently, one after mRNA and the other after the AstraZeneca COVID-19 vaccination. 3,4Flare of other glomerulonephritis has also been reported after different types of COVID-19 vaccination. 5Our second patient reflects that gross haematuria developing shortly after COVID-19 vaccination may reflect or unmask the presence of pre-existing IgA nephropathy.As flare of IgA nephropathy after COVID-19 vaccination is uncommon and mostly benign, it should not be a reason for deterring vaccination.More data on the incidence and significance of acute flare of IgA nephropathy after COVID-19 vaccination will be very useful.