Litcius/Paper detail

Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy

Simon Eschweiler, James Clarke, Ciro Ramírez-Suástegui, Bharat Panwar, Ariel Madrigal, Serena Chee, Ioannis Karydis, Edwin Woo, Aiman Alzetani, Somaia Elsheikh, Christopher J. Hanley, Gareth J. Thomas, Peter S. Friedmann, Tilman Sánchez-Elsner, Ferhat Ay, Christian H. Ottensmeier, Pandurangan Vijayanand

2021Nature Immunology111 citationsDOIOpen Access PDF

Topics & Concepts

CTLA-4Immune checkpointCancer researchPD-L1BlockadeTumor microenvironmentImmunotherapyMelanomaImmunologyImmune systemMedicineBiologyT cellInternal medicineReceptorCancer Immunotherapy and BiomarkersImmune Cell Function and InteractionCAR-T cell therapy research