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PD-1 blockade-unresponsive human tumor-infiltrating CD8+ T cells are marked by loss of CD28 expression and rescued by IL-15

Kyung Hwan Kim, Hong Kwan Kim, Hyung‐Don Kim, Chang Gon Kim, Hoyoung Lee, Ji Won Han, Seong Jin Choi, Seongju Jeong, Minwoo Jeon, Hyunglae Kim, Jiae Koh, Bo Mi Ku, Su‐Hyung Park, Myung‐Ju Ahn, Eui‐Cheol Shin

2020Cellular and Molecular Immunology107 citationsDOIOpen Access PDF

Topics & Concepts

BlockadeCD28CD8Cytotoxic T cellExpression (computer science)Cancer researchTumor-infiltrating lymphocytesCell biologyBiologyImmunologyImmune systemReceptorComputer scienceGeneticsIn vitroProgramming languageCancer Immunotherapy and BiomarkersImmune Cell Function and InteractionImmunotherapy and Immune Responses
PD-1 blockade-unresponsive human tumor-infiltrating CD8+ T cells are marked by loss of CD28 expression and rescued by IL-15 | Litcius