NAD+ precursor supplementation in human ageing: clinical evidence and challenges
Kasper T. Vinten, Maria M. Trętowicz, Evrim Coskun, Michel van Weeghel, Carles Cantó, Rubén Zapata‐Pérez, Georges E. Janssens, Riekelt H. Houtkooper
Topics & Concepts
DiseaseClinical trialMedicineAgeingBioinformaticsBiologyHuman studiesPharmacologyNAD+ kinaseCellular metabolismAnimal studiesTherapeutic approachEndocrinologyLongevityMetabolismHuman diseaseInternal medicineComputational biologyNicotinamideMechanism (biology)Sirtuins and Resveratrol in MedicinePARP inhibition in cancer therapyCalcium signaling and nucleotide metabolism