A network pharmacology approach and experimental validation to investigate the anticancer mechanism of Qi-Qin-Hu-Chang formula against colitis-associated colorectal cancer through induction of apoptosis via JNK/p38 MAPK signaling pathway
Yuguang Wu, Yulai Fang, Yanan Li, Ryan Au, Cheng Cheng, Weiyang Li, Feng Xu, Yuan Cui, Lei Zhu, Hong Shen
Topics & Concepts
DrugBankKEGGSystems pharmacologyPharmacologyComputational biologyMechanism (biology)MAPK/ERK pathwayTraditional Chinese medicineInteraction networkMedicineSignal transductionBiologyBioinformaticsDrugGeneGene expressionGeneticsGene ontologyEpistemologyPathologyPhilosophyAlternative medicineFlavonoids in Medical ResearchColorectal Cancer Treatments and StudiesTraditional Chinese Medicine Analysis