Targeting inflammation and redox aberrations by perindopril attenuates methotrexate-induced intestinal injury in rats: Role of TLR4/NF-κB and c-Fos/c-Jun pro-inflammatory pathways and PPAR-γ/SIRT1 cytoprotective signals
Ahmed M. Sayed, Maha M. Abdel‐Fattah, Hany H. Arab, Wafaa R. Mohamed, Emad H. M. Hassanein
Topics & Concepts
PharmacologyPerindoprilInflammationTLR4MedicineMethotrexateNF-κBChemistryEndocrinologyInternal medicineBlood pressureChemotherapy-induced organ toxicity mitigationChemotherapy-induced cardiotoxicity and mitigationRenin-Angiotensin System Studies