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Trehalose Recycling Promotes Energy-Efficient Biosynthesis of the Mycobacterial Cell Envelope

Amol Arunrao Pohane, Caleb R. Carr, Jaishree Garhyan, Benjamin M. Swarts, M. Sloan Siegrist

2021mBio39 citationsDOIOpen Access PDF

Abstract

The mycomembrane layer of the mycobacterial cell envelope is a barrier to environmental, immune, and antibiotic insults. There is considerable evidence of mycomembrane plasticity during infection and in response to host-mimicking stresses.

Topics & Concepts

TrehaloseImmune systemCell envelopeMicrobiologyEnvelope (radar)Cell wallChemistryCell biologyBiologyImmunologyBiochemistryComputer scienceRadarTelecommunicationsEscherichia coliGeneMycobacterium research and diagnosisAntibiotic Resistance in BacteriaTuberculosis Research and Epidemiology
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