Mitochondrial transplantation: the advance to therapeutic application and molecular modulation
James D. McCully, Pedro J. del Nido, Sitaram M. Emani
Abstract
Mitochondrial transplantation provides a novel methodology for rescue of cell viability and cell function following ischemia-reperfusion injury and applications for other pathologies are expanding. In this review we present our methods and acquired data and evidence accumulated to support the use of mitochondrial transplantation.
Topics & Concepts
TransplantationReperfusion injuryMedicineMitochondrionViability assayIschemiaCellBioinformaticsNeuroscienceBiologyCell biologyCardiologyInternal medicineBiochemistryMitochondrial Function and PathologyCardiac Ischemia and ReperfusionOrgan Transplantation Techniques and Outcomes