Identifying the mechanism underlying antidepressant-like effects of loganin by network pharmacology in combination with experimental validation
Cong‐Yuan Xia, Jie‐Kun Xu, Li Li, Wenwen Lian, Yu Yan, Bing-Zhi Ma, Jun He, Wei-Ku Zhang
Topics & Concepts
LoganinKEGGPharmacologyInflammationMicrogliaAntidepressantNeuroinflammationMedicineBiologyNeuroscienceChemistryImmunologyGene expressionTranscriptomeBiochemistryHippocampusGeneChromatographyHigh-performance liquid chromatographyTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsTreatment of Major Depression