Genome-wide Association Study Identifies HLA-DPB1 as a Significant Risk Factor for Severe Aplastic Anemia
Sharon A. Savage, Mathias Viard, Colm Ó’hUigín, Weiyin Zhou, Meredith Yeager, Shengchao Alfred Li, Tao Wang, Veron Ramsuran, Nicolas Vince, Aurélie Vogt, Belynda Hicks, Laurie Burdett, Charles C. Chung, Michael Dean, Kelvin C. de Andrade, Neal D. Freedman, Sonja I. Berndt, Nathaniel Rothman, Qing Lan, James R. Cerhan, Susan L. Slager, Yawei Zhang, Lauren R. Teras, Michael Haagenson, Stephen J. Chanock, Stephen R. Spellman, Youjin Wang, Amanda Willis, Medhat Askar, Stephanie J. Lee, Mary Carrington, Shahinaz M. Gadalla
Topics & Concepts
Odds ratioAplastic anemiaBiologyHuman leukocyte antigenSingle-nucleotide polymorphismGeneticsMajor histocompatibility complexAllelePancytopeniaCompound heterozygosityImmunologyInternal medicineGeneMedicineGenotypeBone marrowAntigenHematopoietic Stem Cell TransplantationPrenatal Screening and DiagnosticsGenomic variations and chromosomal abnormalities